Detection of SOS function induced by chemical mutagens using umu-test kit.
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Suppression of mutagens-induced SOS response by phytoncide solution using Salmonella typhimurium TA1535/pSK1002 umu test.
Four types of phytoncide solution (A-Type, AB-Type, D-Type and G-Type) were evaluated as antimutagenic agents with suppressive effects on the SOS-inducing activity of the mutagen 2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide (furylfuramide) using Salmonella typhimurium TA1535/pSK1002 umu test. The A-Type, AB-Type, D-Type and G-Type of phytoncide solution suppressed the SOS-inducing activity on fur...
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A methanol extract from Scrophulia ningpoensis showed suppressive effect of the SOS-inducing activity of the mutagen 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide (furylfuramide) in the Salmonella typhimurium TA1535/pSK1002 umu test. The methanol extract was re-extracted with hexane, dichloromethane, butanol, and water. An acidic fraction of the dichloromethane fraction showed a suppressive effect....
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The SOS/umu genotoxicity assay evaluates the primary DNA damage caused by chemicals from the β-galactosidase activity of S. typhimurium. One of the weaknesses of the common umu test system based on spectrophotometric detection is that it is unable to measure samples containing a high concentration of colored dissolved organic matters, sediment, and suspended solids. However, umu tests with elec...
متن کاملMethods for Detection of Chemical Mutagens
O'NEIL, J. 1956 Master's Thesis, Department of Food Technology, Massachusetts Institute of Technology, Cambridge, Mass. PALADINO, S., UGOLINI, F., AND CHAIN, E. B. 1954 Fermentors of 90 and 300 L capacity for vortex and sparger aeration. Rend. Ist. Super. Sanith. 17, 87-120. (Eng. Ed.). PFEIFER, V. F., VOJNOVICH, C., AND HEGER, E. N. 1952 Itaconic acid by fermentation with Aspergillus terreus. ...
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The effect of chemical mutagens on the induction of mitotic chromosomal aberrations in diploid Allium cepa and tetraploid Allium vineale has been studied. In inducing chromosomal aberrations in case of both diploid and tetraploid Allium all the mutagens were found to be effective . Mitotic irregularities were higher in tetraploid species as compared with the diploid species. All types of chemic...
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ژورنال
عنوان ژورنال: Sangyo Igaku
سال: 1986
ISSN: 0047-1879,1881-1302
DOI: 10.1539/joh1959.28.366